| |
Pancreatobiliary type
|
|---|
|
OS
|
RFS
|
|---|
| |
Univariable
|
Multivariable
|
Univariable
|
Multivariable
|
|---|
|
Age
|
0.99 (0.96-1.02)
|
1.02 (0.99-1.05)
|
0.98 (0.96-1.01)
|
0.99 (0.96-1.02)
|
|
Sex
| | | | |
|
Women
| | | | |
|
Men
|
1.24 (0.80-1.91)
|
1.02 (0.64-1.64)
|
1.09 (0.72-1.66)
|
0.82 (0.52-1.30)
|
|
Tumour size
| | | | |
| |
1.03 (1.01-1.05)
|
1.01 (0.99-1.04)
|
1.04 (1.02-1.05)
|
1.01 (0.99-1.04)
|
|
Tumour grade
| | | | |
|
Well-moderate
| | | | |
|
Poor
|
2.50 (1.54-4.05)
|
2.10 (1.28-3.45)
|
2.40 (1.50-3.83)
|
2.35 (1.43-3.84)
|
|
Tumour origin
| | | | |
|
Ampulla
| | | | |
|
Distal bile duct
|
0.74 (0.40-1.34)
|
1.02 (0.53-1.98)
|
1.10 (0.61-1.97)
|
2.68 (0.33-21.81)
|
|
Pancreas
|
0.88 (0.49-1.60)
|
1.08 (0.56-2.08)
|
1.01 (0.56-1.84)
|
2.26 (0.27-18.81)
|
|
T-stage
| | | | |
|
T1
| | | | |
|
T2
|
1.93 (0.23-16,04)
|
0.54 (0.06-5.05)
|
2.21 (0.27-18.38)
|
0.61 (0.06-5.75)
|
|
T3
|
3.99 (0.55-28.85)
|
0.74 (0.09-6.10)
|
6.43 (0.89-46.43)
|
1.28 (0.16-10.29)
|
|
T4
|
5.11 (0.67-38.79)
|
2.36 (0.11-49.41)
|
5.95 (0.78-45.43)
|
0.93 (0.11-8.00)
|
|
N-stage
| | | | |
|
N0
| | | | |
|
N1
|
2.55 (1.49-4.38)
|
2.49 (1.42-4.38)
|
2.59 (1.55-4.33)
|
2.15 (1.22-3.80)
|
|
Margin status
| | | | |
|
R0
| | | | |
|
R1-Rx
|
4.02 (0.99-16.38)
|
2.43 (0.59-10.02)
|
2.71 (0.99-7.44)
|
2.30 (0.82-6.50)
|
|
Perineural
| | | | |
|
Pn0
| | | | |
|
Pn1
|
1.97 (1.10-3.53)
|
1.04 (0.50-2.15)
|
3.09 (1.66-5.75)
|
1.80 (0.94-3.46)
|
|
Lymphatic vessels
| | | | |
|
L0
| | | | |
|
L1
|
1.57 (0.96-2.56)
|
1.02 (0.57-1.85)
|
1.85 (1.14-3.01)
|
1.14 (0.65-2.00)
|
|
Blood vessels
| | | | |
|
V0
| | | | |
|
V1
|
2.43 (1.56-3.78)
|
2.53 (1.59-4.03)
|
2.35 (1.50-3.69)
|
1.96 (1.21-3.17)
|
|
Peripancreatic fat
| | | | |
|
Pn0
| | | | |
|
Pn1
|
1.89 (1.05-3.40)
|
0.94 (0.47-1.90)
|
2.75 (1.50-5.02)
|
1.78 (0.94-3.40)
|
|
SATB1
| | | | |
|
Negative
| | | | |
|
Positive
|
2.11 (1.25-3.56)
|
1.79 (1.05-3.05)
|
1.87 (1.10-3.18)
|
1.54 (0.89-2.66)
|
|
Adjuvant chemotherapy
| | | | |
|
None/other
| | | | |
|
Gemcitabine
|
0.76 (0.49-1.18)
|
0.56 (0.35-0.89)
|
0.98 (0.64-1.49)
|
0.72 (0.46-1.12)
|
- Bold text indicates significant values.
