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Table 2 Multivariate Cox regression analysis of TCTN1 expression in GBM patients of 3 independent cohorts

From: Expression and prognostic significance of TCTN1 in human glioblastoma

Cohort Characteristics Multivariate cox regression
HR (95% CI) P
Chinese GBM (OS) TCTN1 (high vs. low) 1.69 (1.03-2.76) 0.037
  Age (≥53 vs. <53) 1.54 (1.02-2.33) 0.038
(PFS) TCTN1 (high vs. low) 1.60 (1.01-2.52) 0.044
  Age (≥53 vs. <53) 1.46 (0.98-2.18) 0.061
TCGA (OS) TCTN1 (high vs. low) 1.26 (1.03-1.54) 0.026
  Age (≥60 vs. <60) 1.90 (1.55-2.33) <0.001
REMBRANDT (OS) TCTN1 (high vs. low) 1.58 (1.09-2.29) 0.017
  Age (≥60 vs. <60) 2.23 (1.57-3.16) <0.001
  1. Abbreviations: OS, overall survival; PFS, progression-free survival; CI, confidence interval; HR, hazard ratio.