Figure 4

The effect of gC1qR on HPV-16 E2-induced apoptotic death of cells. C33a and SiHa cells (2 × 10⁶) were treated with plain medium, HPV-16 E2 vector, HPV-16 E2 vector + gC1qR siRNA vector, or HPV-16 E2 vector + negative siRNA vector. At 48 h post-transfection, the cells were subjected to flow cytometry analysis to detect the levels of apoptosis. The data represent the means ± SD. These data are representative of three independent experiments. ***p < 0.001, ^# p > 0.05 versus plain medium group (control); ^▲▲▲ p < 0.001 versus the HPV-16 E2 group, ^ΔΔΔ p < 0.001 versus the HPV-16 E2 + gC1qR siRNA group.