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Figure 1 | Journal of Translational Medicine

Figure 1

From: The role of the globular heads of the C1q receptor in HPV-16 E2-induced human cervical squamous carcinoma cell apoptosis via a mitochondria-dependent pathway

Figure 1

The level of HPV-16 E2 and gC1qR protein in human cervical tissue. A: Relative HPV-16 E2 protein levels are shown between human cervical squamous cell carcinoma tissues (T) and non-cancerous cervix tissues from patients who have had a hysterectomy for hysteromyoma or adenomyosis etc (N). The expression of the HPV-16 E2 protein was measured using western blot analysis. The graph shows the relative HPV-16 E2 protein levels, which were quantified and normalised to β-actin. The results shown are the mean ± SD of 30 independent experiments (n = 30), each conducted in triplicate. Students t-test: T versus N. **p < 0.01. B: The gC1qR levels in human cervical tissue. The results of immunohistochemical staining. The positive results for the gC1qR antigen in human cervical tissues by immunohistochemistry (200X). a: Staining of the monoclonal anti-gC1qR antibody in human cervical squamous cell carcinoma tissues. b: Staining of the monoclonal anti-gC1qR antibody in non-cancerous cervix tissues. C: Relative gC1qR expression levels are shown between human cervical squamous cell carcinoma tissues (T) and non-cancerous cervix tissues (N). a: The mRNA expression level of gC1qR was analysed by real-time PCR. b: The expression of the gC1qR protein was measured using western blot analysis. The graph displays the relative gC1qR protein levels normalised to β-actin. The results shown are the mean ± SD of 30 independent experiments (n = 30), each conducted in triplicate. Student's t-test: N versus T. ***p < 0.001.

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