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Figure 1 | Journal of Translational Medicine

Figure 1

From: Collagen II antibody-induced arthritis in Tg1278TNFko mice: optimization of a novel model to assess treatments targeting human TNFα in rheumatoid arthritis

Figure 1

CAIA in wild type and Tg1278TNFko animals. Arthritis was induced in male mice by i.p. injection of 2, 4 or 8 mg collagen II antibody cocktail (CAb) on Day 0 followed by 100 μg LPS i.p. 4 days later. A, Arthritis scores of wild type animals. B, arthritis scores of Tg1278TNFko animals. C, Bodyweights of wild type animals. D, bodyweights of Tg1278TNFko animals. Data are means +/- s.e.m., n = 6-8/group.

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Journal of Translational Medicine

ISSN: 1479-5876

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