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Table 4 The reproducibility of DIPS for triplicate testing of cytological samples after a one-month preservation*

From: Diagnosis of 25 genotypes of human papillomaviruses for their physical statuses in cervical precancerous/cancerous lesions: a comparison of E2/E6E7 ratio-based vs. multiple E1-L1/E6E7 ratio-based detection techniques

DIPS rounds First-round DIPS (+) (n = 357) First-round DIPS (−) (n = 805)
E2/E6E7 ratio analysis (+) & E1-L1/E6E7 ratio analysis (+) (n = 6) E2/E6E7 ratio analysis (+) & E1-L1/E6E7 ratio analysis (+) (n = 2) E2/E6E7 ratio analysis (-) & E1-L1/E6E7 ratio analysis (-) (n = 797)
Second-round Confirmed: 299 Confirmed: 5 Confirmed: 2 Confirmed: 797
Denied: 58 Denied: 1 Denied: 0 Denied: 0
Reproducibility between 1st- and 2nd-round DIPS: 94.9%
Third-round Confirmed: 281 Confirmed: 5 Confirmed: 1 Confirmed: 797
Denied: 76 Denied: 1 Denied: 1 Denied: 0
Reproducibility between 1st- and 3rd-round DIPS: 93.3%
Second- and Third-round Consistently confirmed: 278 Consistently confirmed: 4 Consistently confirmed: 1 Consistently confirmed: 797
General reproducibility: 92.9%
  1. *The reproducibility was calculated by dividing the number of cases that were confirmed by two or three rounds of DIPS by the total number (n = 1162) of tested cases.