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Figure 2 | Journal of Translational Medicine

Figure 2

From: Diagnosis of 25 genotypes of human papillomaviruses for their physical statuses in cervical precancerous/cancerous lesions: a comparison of E2/E6E7 ratio-based vs. multiple E1-L1/E6E7 ratio-based detection techniques

Figure 2

The relationship between cervical lesions and HPV integration. A. The age-related distribution patterns of cervical lesions (upper panel) and HPV integration events (lower panel, detected with DIPS) in the enrolled women. A significant time retardation was observed between women with cervical precancerous/cancerous lesions and those without lesions as well as between women with cervical integrated/mixed HPV infections and those with episomal infections. B. The cervical lesion-related distribution pattern of HPV integration is displayed. C. The relationship between the HPV integration rate and its tumorigenic rates was analyzed using the Pearson's product–moment correlation coefficient, r. Blue line, the linear fitting curve.

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