Figure 6
From: let-7b/g silencing activates AKT signaling to promote gastric carcinogenesis
AKT2 re-expression rescues the inhibitory effect of let-7b/g. (A) AKT2 re-expression partly abolished the growth-inhibitory effect of let-7b/g in a 5-day MTT assays (*, P < 0.05; **, P < 0.001). The SDs were achieved by the 575 nm absorbance readings in 6 wells of each item. (B) AKT2 abrogated the suppressed monolayer colony formation by let-b/g (*, P < 0.05; **, P < 0.001). The experiments was performed in triplicate wells to get SDs. (C) AKT2 re-expression promoted in vivo tumor growth (**, P < 0.001).