Figure 1

let-7b/g is down-regulated in in gastric cancer and correlates with poor survival. (A) The expression of let-7b/g in 9 gastric cancer cell lines compared with normal gastric epithelium tissue (AM7996). (B) let-7b/g showed a decreased expression in primary gastric tumors compared with paired adjacent non-tumours tissues (n = 76; let-7b, P = 0.013; let-7g, P = 0.003). (C) Downregulation of let-7b/g predicted poorer survival in clinical gastric cancer patients (let-7b, P = 0.001; let-7g, P = 0.051).