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Figure 5 | Journal of Translational Medicine

Figure 5

From: Propofol exerts anti-hepatocellular carcinoma by microvesicle-mediated transfer of miR-142-3p from macrophage to cancer cells

Figure 5

miR-142-3p was involved in the effect of propofol on anti-tumor activity. (A) The expression of miR-142-3p was detected in Raw 264.7 cells transfected with miR-142-3p inhibitor. (B) The expression of miR-142-3p was measured in MVs from Raw 264.7 cells transfected with miR-142-3p inhibitor. The expression of miR-142-3p (C) and the invasion ability (D) were detected in Hepa1-6 cells treated with MVs from Raw 264.7 cells transfected with Nc or miR-142-3p inhibitor. (E) Tumor sizes and (F) tumor weights were measured in tumor-bearing mice injected with Nc or miR-142-3p inhibitor. *P < 0.05, **P < 0.01 indicate significant differences from control group. #P < 0.05, ##P < 0.01 indicate significant differences from propofol group.

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