Figure 6

Model for regulation of MMP-9, MMP-13 and EMMPRIN by curcumin. PMA induced EMMPRIN, MMP-9 and MMP13 expression by macrophages through AMPK and PKC pathway.Curcumin attenuates expression of MMP-9, MMP-13 and EMMPRIN by inhibiting the activation of AMPK and PKC pathway.