Figure 6

Spectrum of metabolic persister genes in Mtb and pathway distribution of potential non-toxic drug targets. A) Spectrum of metabolic persister genes in Mtb. X-axis represents the total number of gene knockouts. Total number of MPG for respective knockout is shown above x-Axis and total number of affected genes is shown below x-axis (B) For both A and B the respective box-plots are shown with the region below median colored red representing genes of interest. C) Pathway level coverage of essential genes: All the essential genes and the metabolic persisters genes are plotted relative to total number of genes in a given pathway.