Figure 5
The effects of LRP6 and PIK3R2 alterations on miR-126-3p functions in Hep-G2 cells. (A, B) Both invasion and migration assays showed that the trans-cells of the “rescue” group (anti-126 + si-LRP6) significantly reduced compared with anti-126 group (C) Tube formation assays showed that the group co-transfected with PIK3R2 and 126-mimics formed more tube branches than 126-mimics group (D) Western bolt was performed to assess the protein levels of LRP6 and PIK3R2 in co-transfection assays. NC indicated negative control, *P < 0.05. **P < 0.01.