Skip to main content

Table 2 Cox regression analysis, recurrence free cancer specific survival (n = 560 in the multiple analysis)

From: The prognostic value of microRNA-126 and microvessel density in patients with stage II colon cancer: results from a population cohort

  Simple analysis Multiple analysis
  HR 95% CI p-value HR 95% CI p-value
Sex       
Female 1      
Male 1.16 0.81-1.67 0.41    
Age, median 74       
<74 1      
≥74 1.14 0.80-1.64 0.47    
T category       
T3 1    1   
T4 3.65 2.46-5.43 <0.0001 2.69 1.74-4.16 <0.0001
Malignancy grade       
Medium + Low 1    1   
High* 1.49 0.98-2.27 0.06 1.42 0.92-2.18 0.11
Localisation       
Right 1      
Left 1.12 0.78-1.60 0.54    
Perforation       
No 1    1   
Yes 3.66 2.34-5.73 <0.0001 2.57 1.54-4.30 0.0003
Fixation       
No 1    1   
Yes 2.49 1.69-3.67 <0.0001 1.32 0.83-2.10 0.23
Lymph nodes       
≥12 1      
<12 0.85 0.59-1.22 0.37    
Neuronal invasion       
No 1    1   
Yes 2.05 1.24-3.38 0.005 1.46 0.84-2.55 0.18
Vascular invasion       
No 1    1   
Yes 2.00 1.27-3.16 0.003 1.61 1.00-2.61 0.05
MSI status       
MSI 1      
MSS 1.39 0.90-2.15 0.14    
miRNA-126       
<median 1    1   
>median 0.72 0.50-1.04 0.08 0.96 0.66-1.40 0.83
MVD       
<median 1      
>median 0.88 0.61-1.26 0.49    
  1. HR: hazard ratio; CI: confidence interval; MSI: microsatellite instability; MSS: microsatelite stable; miRNA-126: microRNA-126; MVD: microvessel density.
  2. *Including mucinous and sigillocellular adenocarcinomas.
  3. Significant p-values are highlighted in bold.