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Table 3 Association between PPARγ2 CG/GG genotype (Ala variant) and HOMA-IR in HIV/HCV coinfected patients

From: PPARγ2 Pro12Ala polymorphism was associated with favorable cardiometabolic risk profile in HIV/HCV coinfected patients: a cross-sectional study

 

CC

CG/GG

p-value(a)

aAMR (95% CI)

p-value(b)

All patients

2.1 (2.4)

1.7 (2.3)

0.839

0.89 (0.66; 1.20)

0.452

Patients with F < 2

1.8 (1.8)

1.3 (1.5)

0.681

1.01 (0.61; 1.65)

0.988

Patients with F ≥ 2

2.5 (3.3)

2.3 (1.9)

0.025

0.69 (0.49; 0.98)

0.038

  1. Values expressed as median [interquartile range = upper quartile (Q3) - lower quartile (Q1)] and adjusted arithmetic mean ratio (aAMR) [95% of confidence interval (95% CI)]. Statistically significant differences are shown in bold. (a)P-values were calculated by generalized linear models (GLM) with gamma distribution (log-link). (b)P-values were calculated by GLM with log-link adjusted by the most important clinical and epidemiological characteristics (see Statistical analysis section).
  2. Abbreviations: HCV hepatitis C virus, HIV human immunodeficiency virus, HOMA homeostatic model assessment.