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Table 2 Univariate and multivariate logistic regression analysis of factors associated with pathologic response

From: Association of decreased expression of long non-coding RNA LOC285194 with chemoradiotherapy resistance and poor prognosis in esophageal squamous cell carcinoma

    

Univariate analysis

Multivariate analysis

Variables

Case

PathCR

<pathCR

OR

95% CI

pvalue

OR

95% CI

pvalue

Ages

         

≤55

12

2

10

0.278

0.054-1.424

0.125

0.302

0.049-1.874

0.199

>55

43

18

25

      

Gender

         

Male

34

9

25

0.372

0.104-1.030

0.056

0.415

0.103-1.676

0.217

Female

21

11

10

      

Tumor size (cm)

         

≤5

35

14

21

1.556

0.482-5.019

0.460

0.617

0.131-2.905

0.541

>5

20

6

14

      

Tumor location

         

Cervical/upper thoracic

14

7

7

2.154

0.625-7.421

0.224

1.757

0.372-8.298

0.477

Middle/lower thoracic

41

13

28

      

Histologic grade

         

G1

8

3

5

0.873

0.172-4.429

0.870

nd

nd

nd

G2

27

11

16

1.400

0.250-7.830

0.702

nd

nd

nd

G3

20

6

14

      

T status

         

T1/2

14

6

8

1.446

0.419-4.997

0.560

nd

nd

nd

T3

41

14

27

      

N status

         

Negative

20

10

10

2.500

0.797-7.839

0.116

0.508

0.027-9.577

0.651

Positive

35

10

25

      

M status

         

M0

39

16

23

2.087

0.586-7.651

0.267

1.250

0.212-7.368

0.805

M1-lym

16

4

12

      

Clinical stage

         

IandII

21

10

11

2.182

0.705-6.756

0.176

2.102

0.109-40.483

0.623

III

34

10

24

      

LOC285194

         

low

27

4

23

0.130

0.036-0.478

0.002*

0.133

0.028-0.624

0.011*

high

28

16

12

      
  1. PathCR, pathologic complete response; OR, odd ratio; CI, confidence interval; M1-lym, distant lymph node metastasis; nd, not done. *p < 0.05.
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Journal of Translational Medicine

ISSN: 1479-5876

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