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Table 2 Biochemical and Hematological Parameters

From: Fluid resuscitation therapy in endotoxemic hamsters improves survival and attenuates capillary perfusion deficits and inflammatory responses by a mechanism related to nitric oxide

 

LPS

LPS/FR

LPS/FR/LNNA

Arterial lactate (mmol.l−1)

7.92 ± 1.30

3.42 ± 0.44*

3.56 ± 0.73*

pH

7.25 ± 0.04

7.33 ± 0.03*

7.18 ± 0.07*§

Bicarbonate (mmol.l−1)

21.50 ± 1.00

23.25 ± 0.95

22.95 ± 3.30

Base excess (mmol.l−1)

−4.7 ± 3.3

−2.1 ± 0.9*

−4.4 ± 0.3§

Hematocrit (%)

55.75 ± 1.70

50.00 ± 2.70*

47.70 ± 1.33*

Blood Glucose (mg.dl−1)

32.00 ± 9.20

45.00 ± 11.22*

38.20 ± 7.48

Leukometry (n/mm3)

1,553 ± 493

3,305 ± 675*

2,330 ± 457

  1. Blood sampling for biochemical and hematological analysis was performed in all groups at the end of the study period (t = 3 h). Data are presented as means ± SD for each group. LPS, endotoxemic animals (n = 10); LPS/FR, endotoxemic and fluid resuscitated animals (n = 10); LPS/FR/LNNA, endotoxemic, fluid resuscitated, and L-NNA + L-Arginine treated animals (n = 10). *p <0.05 vs. LPS group; §p <0.05 vs. LPS/FR group.