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Table 1 Base-line characteristics of the 11 patients with HBV-associated HCC

From: Viral expression and molecular profiling in liver tissue versus microdissected hepatocytes in hepatitis B virus - associated hepatocellular carcinoma

Characteristic

 

Age, yr

57.7 ± 7.7

Male, No. (%)

10 (90.9)

Alanine aminotransferase, U/L a

36.18 ± 17.8

Aspartate aminotransferase, U/L b

39.09 ± 17.0

Total bilirubin, mg/dL

0.88 ± 0.47

Albumin, g/dL c

3.91 ± 0.57

γ-glutamyltransferase, U/L

93.9 ± 83.56

Prothombin time, INR e

1.13 ± 0.14

Platelet count, per mm 3

153,81 ± 93,73

α-fetoprotein, ng/mL d

 

 Normal, No.

8

 Abnormal, No.

2

Non-tumorous tissue

 

 Activity Grade

5.75 ± 3.06

 Fibrosis Stage

5.1 ± 1.56

 F5/F6, No.

9

Tumor Gradef

 G2, No.

7

 G3, No.

3

 G4, No.

1

Tumor size

 

 ≥2 cm, No.

4

 ≥2 and ≤ 3 cm, No.

4

 >3 cm, No.

3

HBsAg-positive, No.

11

HBeAg-positive, No.

0

Anti-HBc, No.

11

Anti-HBe, No.

11

IgG anti-HDAg positive, No.

1

IgM anti-HDAg, No.

0

Serum HDV RNA positive, No.

0

Anti-HCV positive, No.

1

Serum HCV RNA positive, No.

0

  1. NOTE. Plus-minus values are means ± SD. To convert values for total bilirubin to micromoles per liter, multiply by 17.1. HBsAg, hepatitis B surface antigen; HBeAg, hepatitis B e antigen; HDAg, hepatitis delta antigen; HBV, hepatitis B virus; and HDV, hepatitis D virus.
  2. aNormal range, ≤43 U per liter.
  3. bNormal range, ≤42 U per liter.
  4. cNormal range, ≥3.6 - ≤5.0.
  5. dNormal range, <10.0 ng/mL. Data were not available from one patient.
  6. eNormal range, 0.80-1.20 international normalized ratio (INR).
  7. fTumors were graded using the Edmondson-Steiner criteria.