Figure 4

HBV DNA levels in liver and serum of patients with HBV-associated HCC. (A) HBV DNA levels in different areas of the liver, within the center (A) and the periphery of the tumor (B) and progressively distal to the tumor (C and E), as measured by real-time PCR in 11 patients with HBV-associated HCC. (B) HBV DNA levels in serum of patients with HBV-associated HCC. Quantities are expressed as Log₁₀ IU/ng (liver) or Log₁₀ IU/mL (serum) as compared to an international HBV DNA standard. The levels of HBV DNA in the different areas of the liver and in serum are shown as median ± interquartile range. Liver samples for HBV DNA quantification from areas B and C were available in only 8 patients.