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Figure 3 | Journal of Translational Medicine

Figure 3

From: Identification of novel epitopes from human papillomavirus type 18 E7 that can sensitize PBMCs of multiple HLA class I against human cervical cancer

Figure 3

EBV-BCLs cytotoxicity of PBMCs sensitized with HPV 18 E7 81-95 (#21) and E7 89-103 (#23) peptides. HPV18 E781-95 (#21)- and E789-103 (#23)-sensitized CTLs lysed more EBV-BLCs with E781-95 (#21) and E789-103 (#23), respectively, than negative control (EBV-BLCs with no peptide) in all HLA-A*02:01 (A), A*24:02 (B), A*11:01(C), A*33:03 (D). PBMCs sensitized with E781-95 or E789-105 with EBV-BCLs loaded with no peptide or PBMCs sensitized with no peptide and E789-105-loaded EBV-BCLs were used as negative controls. Data are representative of at least three independent experiments using PBMCs from HLA-A*02:01, HLA-A*24:02, HLA-A*11:01, HLA-A*33:03 subjects. Data are presented as mean (point) ± standard error (bar).

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