Figure 4
From: Remote ischemic preconditioning preserves Connexin 43 phosphorylation in the rat heart in vivo
Western Blot analysis of Cx43 protein expression. (A) Exemplary original blot showing the expression of Cx43 and Na+/K+-ATPase. The upper Cx43 band represents the expression of phosphorylated Cx43, while the lower band corresponds to dephosphorylated Cx43. (B) Relative expression of total Cx43 protein vs. Na+/K+-ATPase. Cx43 expression is significantly lower in the AAR of I/R hearts compared to Sham. (C) Analysis of phosphorylated vs. dephosphorylated Cx43. The degree of dephosphorylated Cx43 is higher in the AAR of I/R hearts compared to Sham and RIPC + I/R hearts. RIPC = remote ischemic preconditioning, I/R = ischemia and reperfusion, (Data are median, min to max, n = 6 / group. * p < 0.05).