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Table 3 Daily evaluation form sent home and made out by the owners

From: High dose lansoprazole combined with metronomic chemotherapy: a phase I/II study in companion animals with spontaneously occurring tumors

Vomiting

    

None

3 episodes per day

5 episodes per day

>5 episodes per day

>5 per day OR

 

OR

OR

OR

days lasting >4 days and

 

vomiting lasting 2 days

vomiting lasting 4 days

for >4 days

life threatening

Diarrhea

    

None

2 more stools

6 more stools

>6 more stools

>6 and life

 

than normal

than normal

than normal

hospitalized

Nausea

    

None

Appetite loss with

Salivating or lip

Salivation or lip

Salivation/lip

 

normal eating habits

smacking for 12 hrs

smacking for 24 hrs

smacking >24 h

Appetite

    

Normal

With treats or diet

Appetite loss for 3 days OR

Appetite loss for 5 days OR

Loss >5 days

 

change, ate 100%

With treats or diet

With treats or diet

OR

  

change, ate 50% of normal

change, ate few bites

No interest,

    

no appetite

Flatulence

    

Normal

1-2 episodes per day

2-4 episodes per day

4-6 episodes per day

> 6 episodes per day

Activity

    

Normal

Mild lethargy

Moderate lethargy, difficulty

Severe lethargy, only

Unable to

  

with daily activities

gets up to go outside

rise on own