Table 3 Infarct volume, cell death, functional evaluation and post-operative weight loss in the embolic stroke (ES) and the permanent middle cerebral artery occlusion (pMCAO) models

Volume of infarct in percent of the contralateral hemisphere, median (IQR)

58.6 (9.6)

29 (5.1)

<0.001

Cell death as number of TUNEL positive cells

Cortex, median (IQR)

103 (20.1)

133.3 (18.1)

0.022

Striatum, median (IQR)*

59.1 (10.4)

-

-

Functional evaluation**

At 24h, median (IQR)

4 (1)

3 (0)

0.009

At 48 h, median (IQR)

4 (1)

3 (0)

0.009

At 72 h, median (IQR)

4 (1)

3 (1)

0.041

Percent post-operative weight loss, mean (SD)

34.8 (11.5)

42.8 (12)

0.286