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Table 3 Infarct volume, cell death, functional evaluation and post-operative weight loss in the embolic stroke (ES) and the permanent middle cerebral artery occlusion (pMCAO) models

From: Biochemical and inflammatory biomarkers in ischemic stroke: translational study between humans and two experimental rat models

  ES (n = 6) pMCAO (n = 6) P
Volume of infarct in percent of the contralateral hemisphere, median (IQR) 58.6 (9.6) 29 (5.1) <0.001
Cell death as number of TUNEL positive cells    
Cortex, median (IQR) 103 (20.1) 133.3 (18.1) 0.022
Striatum, median (IQR)* 59.1 (10.4) - -
Functional evaluation**    
At 24h, median (IQR) 4 (1) 3 (0) 0.009
At 48 h, median (IQR) 4 (1) 3 (0) 0.009
At 72 h, median (IQR) 4 (1) 3 (1) 0.041
Percent post-operative weight loss, mean (SD) 34.8 (11.5) 42.8 (12) 0.286
  1. *Striatal infarction is only present in the ES model
  2. **Rogers scale score.