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Figure 2 | Journal of Translational Medicine

Figure 2

From: Prostaglandin D2-supplemented “functional eicosanoid testing and typing” assay with peripheral blood leukocytes as a new tool in the diagnosis of systemic mast cell activation disease: an explorative diagnostic study

Figure 2

Basal release of PGD 2 from PBLs of MCAD patients. Data represent individual PGD2 levels of MCAD patients and healthy controls, derived group means (black horizontal lines), and the optimal cut-off value (red horizontal line) of 333.31 pg/ml with 2.3% misclassification. Data were statistically analyzed using the Student’s t-test for unpaired values and ROC analysis, respectively. Control: healthy individuals (n = 20), MCAD: patients with mast cell activation disease (n = 22); (A) MCAS: MCAD patients with mast cell activation syndrome (n = 12); SM: MCAD patients with systemic mastocytosis (n = 10); (B) MCAD-M: MCAD patients without MCAD-specific medication (n = 9); MCAD + M: MCAD patients with MCAD-specific medication (n = 13).

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