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Table 1 Bioinformatic predictors of HIV-1 coreceptor use based on V3 loop sequence.

From: Clinical significance of HIV-1 coreceptor usage

Predictor

URL

Method

Ref

R5/X4 and NSI/SI network

http://cancer.med.unc.edu/swanstromlab/resources.html

Neural network

Resch et al, 2001

WebPSSM

http://indra.mullins.microbiol.washington.edu/webpssm/

http://fortinbras.us/cgi-bin/fssm/fssm.pl

PSSM

Jensen et al, 2003

WetCat

http://genomiac2.ucsd.edu:8080/wetcat/v3.html

SVM

Pillai et al, 2003

Geno2pheno

http://coreceptor.bioinf.mpi-inf.mpg.de/

SVM

Sing et al, 2007

V3SD

The source code for prediction and analysis is available upon request.

SVM

Sander et al, 2007

R5/X4-pred

http://yjxy.ujs.edu.cn/R5-X4pred.rar

Random forests

Xu et al, 2007

ANN

Not available

Neural network

Lamers et al, 2008

hiv-dskernel

http://genome.ulaval.ca/hiv-dskernel

SVM

Boisvert et al, 2008