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Table 3 Tumor gene expression to platinum-containing treatment in responders and non-responders

From: Peritoneal carcinomatosis from ovarian cancer: chemosensitivity test and tissue markers as predictors of response to chemotherapy

 

Median expression values (range)

Gene

Total patients

Responders

Non-responders

p

MGMT

0.90 (0-20.0)

0.57 (0-2.2)

2.0 (0-20.0)

0.03

XPD

0.80 (0.027-12.4)

0.52 (0.027-2.0)

1.9 (0.11-12.4)

0.04

BRCA1

2.60 (0-87.4)

1.73 (0.20-6.47)

3.0 (0-87.4)

0.59

ERCC1

1.50 (0.47-15.0)

2.30 (0.7-7.02)

1.4 (0.47-15.0)

0.93

GSTP1

1.75 (0.15-45.0)

1.47 (0.15-7.5)

1.7 (0.71-45.0)

0.65