Table 1 Canonical CD33⁺ human MDSC induction by human cancer cell lines

T cells alone

0.00

** HeLa

68.35

5.36

Medium only

-2.35

0.86

** ME-180

75.24

3.83

Lung Fibroblasts

-1.03

0.96

** SIHA

54.49

8.66

Ditt Fibroblasts

-0.13

2.91

** RL95-2

52.11

3.84

** GM-CSF + IL-6

56.30

5.01

SW 756

-83.60

2.18

HNSCC (6/8)

Ovarian (6/9)

** SCCL-MT1

91.83

0.82

** A2780

64.46

5.33

Irradiated

89.18

0.20

** ES-2

63.62

5.17

T cell Depl.

81.49

4.98

** TOV-21G

52.86

11.37

** USC-HN2 ¹

87.97

ND

** SK-OV-3

51.44

9.81

** SCC-4

65.72

2.08

* NIHOVCAR-3

47.89

1.08

** CAL-27

66.26

6.21

* SW 626

46.54

4.07

** SW 451

59.49

9.59

HOC-7

41.77

19.15

* FaDu

30.98

4.45

HEY

22.20

3.87

RPMI 2650

17.46

5.01

Caov-3

-146.53

2.69

SW 2224

-13.48

11.21

Breast (0/9)

Thyroid (1/2)

MCF-7

16.95

0.39

** SW 579

68.97

3.41

734B

16.72

2.32

SW 1949

43.90

13.68

T47D

8.47

1.23

Brain (2/9)

BT-474

0.83

11.53

** NU-04

69.41

4.02

SKBR3

-0.09

13.53

** U118MG

51.96

1.48

MDA-MB-468

-3.46

0.25

SW 598

14.29

4.14

GI-101

-6.41

0.92

A172

2.26

4.97

SV-BR-1

-8.00

1.75

IMR-5

-1.23

3.09

MDA231

-16.21

2.60

IMR-32

-3.16

7.48

Bladder (1/3)

TE 671

-12.23

4.29

** T24

53.89

3.97

Y79

-72.63

5.58

SW 780

8.10

10.01

BM-166

-83.22

0.05

SW 733

-54.63

0.45

Melanoma (1/3)

Prostate (2/3)

** A375

56.16

0.64

** DU 145

54.73

2.07

CaCl74-36

17.26

6.83

* LNCaP

29.09

2.78

Colo 38

15.83

1.49

PC3

15.12

9.09

Sarcomas (4/9)

Renal (3/6)

** 4-998

58.31

0.82

** 786-O

75.91

6.06

Irradiated

52.10

0.44

** CAKI-1

64.94

3.70

T cell Depl.

65.23

8.17

** CAKI-2

63.62

5.17

* Rh30

44.63

2.51

SW 156

36.51

10.69

* HOS

42.58

4.86

ACHN

9.85

0.20

* SW 1353

42.22

4.42

SK-NEP-1

0.00

1.82

HT 1080

19.37

5.92

Gastric (1/2)

SA-4

12.53

1.05

** SW 1961

64.55

3.04

HS 919

3.01

5.31

KATO-III

7.65

2.16

SW 80

-5.00

3.93

Colorectal (5/6)

HS 913T

-56.35

1.45

** SW 732

69.19

1.29

Lung (4/11)

** DLD-1

65.59

3.19

Non-small cell (2/7)

** SW 608

53.11

5.15

* A427

27.71

6.87

** SW 707

52.38

0.64

* SW 1573

21.47

1.64

* HT-29

38.37

4.91

NCI-H292

8.23

2.89

LS147T

13.62

3.87

NCI-H1650

6.67

4.18

Pancreatic (3/10)

SK-MES-1

4.31

6.03

** SW 1990

78.15

1.21

NCI-H125

1.54

3.69

* Panc 2.03

22.28

4.37

NCI-H1975

0.28

2.89

* Panc 4.14

21.82

2.60

Small Cell 2/3)

Panc 9.6.94

27.28

8.47

** NCI-H464

63.96

6.00

Panc-1

7.82

3.69

* NCI-H60

47.79

7.71

Panc 3.27

6.98

5.44

NCI-HUT 69C

-24.28

16.75

ASPC-1

3.09

2.36

Mesothelioma (0/1)

CAPAN-1

-1.34

2.27

SW 1503

1.93

2.02

Panc 2.5

-1.79

6.08

Liver (2/5)

MIA PaCa-2

-4.38

1.94

* HA 22T

44.01

4.22

Epidermoid (0/1)

* HEP 3B

23.52

7.44

A431

-31.12

8.55

PLC

22.05

5.22

MAH

11.87

4.72

HEP-G2

-2.10

9.40