No relationship between the distribution of mast cells and the survival of stage IIIB colon cancer patients

Table 4 Multivariate Cox analysis of factors associated with OS

Variable	OS (n = 93)
	HR, (95% CI)	P
Age (<60 y vs. ≥60 y)	0.497 (0.219-1.127)	0.094
Gender (female vs. male)	1.302 (0.571-2.969)	0.531
Location of primary tumor (right vs. left)	2.220 (0.922-5.345)	0.075
Pathologic classification (mucoid + signet ring vs. papillary + tubular)	2.514 (0.662-9.537)	0.175
Pathologic grade (G3 vs. G2 + G1)	1.108 (0.300-4.094)	0.877
Growth type (infiltrating vs. pushing)	1.195 (0.489-2.917)	0.696
Invasive depth (T4 vs. T3)	1.456 (0.464-4.569)	0.520
MCC_stroma*(≥2.6 MC/HP vs. <2.6 MC/HP)	1.180 (0.524-2.659)	0.690
MCC_adjacent (≥10.6 MC/HP vs. < 10.6 MC/HP)	0.812 (0.372-1.774)	0.602
MCC_slnm (≥4.0 MC/HP vs. < 4.0 MC/HP)	1.890 (0.748-4.773)	0.178
MCC_alnm (≥5.2 MC/HP vs. <5.2 MC/HP)	0.916 (0.354-2.367)	0.856
MCC_lnwm (≥10.2 MC/HP vs. <10.2 MC/HP)	0.729 (0.329-1.614)	0.436

*: MCC_stroma, the count of tryptase-positive mast cells in the cancer stroma of the primary colon tumor; MCC_adjacent, the count of tryptase-positive mast cells in the normal mucosa adjacent to the colon cancer; MCC_slnm, the count of tryptase-positive mast cells in the stroma of matched lymph node metastasis; MCC_alnm, the count of tryptase-positive mast cells in the normal lymph tissue adjacent to the lymph node metastasis; MCC_lnwm, the count of tryptase-positive mast cells in the regional-draining lymph node without metastasis.

ISSN: 1479-5876