No relationship between the distribution of mast cells and the survival of stage IIIB colon cancer patients

Table 3 Univariate analysis of factors associated with OS

Variable	OS (n = 93)
	HR, (95% CI)	P
Age (<60 y vs. ≥60 y)	0.635 (0.291-1.386)	0.249
Gender (female vs. male)	1.158 (0.537-2.495)	0.707
Location of primary tumor (right vs. left)	1.915 (0.896-4.093)	0.087
Pathologic classification (mucoid + signet ring vs. papillary + tubular)	2.325 (1.043-5.183)	0.033
Pathologic grade (G3 vs. G2 + G1)	1.749 (0.785-3.894)	0.165
Growth type (infiltrating vs. pushing)	0.856 (0.392-1.870)	0.696
Invasive depth (T4 vs. T3)	0.853 (0.295-2.466)	0.768
MCC_stroma *(≥2.6 MC/HP vs. <2.6 MC/HP)	1.224 (0.573-2.615)	0.600
MCC_adjacent (≥10.6 MC/HP vs. < 10.6 MC/HP)	0.943 (0.443-2.006)	0.878
MCC_slnm (≥4.0 MC/HP vs. < 4.0 MC/HP)	1.588 (0.727-3.469)	0.241
MCC_alnm (≥5.2 MC/HP vs. <5.2 MC/HP)	1.045 (0.491-2.223)	0.909
MCC_lnwm (≥10.2 MC/HP vs. <10.2 MC/HP)	0.779 (0.365-1.665)	0.518

*: MCC_stroma, the count of tryptase-positive mast cells in the cancer stroma of the primary colon tumor; MCC_adjacent, the count of tryptase-positive mast cells in the normal mucosa adjacent to the colon cancer; MCC_slnm, the count of tryptase-positive mast cells in the stroma of matched lymph node metastasis; MCC_alnm, the count of tryptase-positive mast cells in the normal lymph tissue adjacent to the lymph node metastasis; MCC_lnwm, the count of tryptase-positive mast cells in the regional-draining lymph node without metastasis.

ISSN: 1479-5876