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Table 2 Correlations between various MCCs and clinicopathologic characteristics

From: No relationship between the distribution of mast cells and the survival of stage IIIB colon cancer patients

Variable

n

MCCstroma*

P

MCCadjacent

P

MCCslnm

P

MCCalnm

P

MCClnwm

P

  

<2.6 ≥2.6

 

<10.6≥10.6

 

<4.0 ≥4.0

 

<5.2 ≥5.2

 

<10.2 ≥10.2

 

Age

  

0.243

 

0.911

 

0.377

 

0.121

 

0.471

   < 60

43

18 25

 

21 22

 

22 21

 

25 18

 

23 20

 

   ≥60

50

27 23

 

25 25

 

21 29

 

21 29

 

23 27

 

Gender

  

0.407

 

0.574

 

0.726

26

0.250

 

0.045

   Male

58

30 28

 

30 28

 

26 32

 

26 32

 

24 34

 

   Female

35

15 20

 

16 19

 

17 18

 

20 15

 

22 13

 

Location of primary tumor

  

0.431

 

0.336

 

0.094

 

0.588

 

0.472

   Left

54

28 26

 

29 25

 

21 33

 

28 26

 

25 29

 

   Right

39

17 22

 

17 22

 

22 17

 

18 21

 

21 18

 

Pathologic classification

  

0.732

 

0.652

 

0.900

 

0.038

 

0.576

Papillary + tubular

73

36 37

 

37 36

 

34 39

 

32 41

 

35 38

 

Mucoid + signet ring

20

9 11

 

9 11

 

9 11

 

14 6

 

11 9

 

Pathologic Grade

  

0.799

 

0.998

 

0.991

   

0.582

   G1

2

1 1

 

1 1

 

1 1

 

0 2

0.001

1 1

 

   G2

69

32 37

 

34 35

 

32 37

 

28 41

 

32 37

 

   G3

22

12 10

 

11 11

 

10 12

 

18 4

 

13 9

 

Growth type

  

1.000

 

0.769

 

0.239

   

0.769

   Pushing

31

15 16

 

16 15

 

17 14

 

18 13

 

16 15

 

   Infiltrating

62

30 32

 

30 32

 

26 36

 

28 34

0.241

30 32

 

Invasive depth

  

0.683

 

0.293

 

0.826

   

0.615

   T3

77

38 39

 

40 37

 

36 41

 

39 38

 

39 38

 

   T4

16

7 9

 

6 10

 

7 9

 

7 9

0.615

7 9

 
  1. *: MCCstroma, the count of tryptase-positive mast cells in the cancer stroma of the primary colon tumor; MCCadjacent, the count of tryptase-positive mast cells in the normal mucosa adjacent to the colon cancer; MCCslnm, the count of tryptase-positive mast cells in the stroma of matched lymph node metastasis; MCCalnm, the count of tryptase-positive mast cells in the normal lymph tissue adjacent to the lymph node metastasis; MCClnwm, the count of tryptase-positive mast cells in the regional-draining lymph node without metastasis.