Figure 6From: Inhibition of mitotic kinase Aurora suppresses Akt-1 activation and induces apoptotic cell death in all-trans retinoid acid-resistant acute promyelocytic leukemia cellsMorphological changes in nucleus after induction of apoptosis by VX-680. (A) VX-680 treated or untreated cells were stained with Hoechst 33342, and observed by fluorescence microscopy (magnification, 400×). (B) Data summarized three independent experiments, ***p < 0.001, compared to control.Back to article page