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Figure 5 | Journal of Translational Medicine

Figure 5

From: Inhibition of mitotic kinase Aurora suppresses Akt-1 activation and induces apoptotic cell death in all-trans retinoid acid-resistant acute promyelocytic leukemia cells

Figure 5

VX-680 induces apoptosis of NB4-R2 cells by Annexin V/PI staining. NB4-R2 cells were treated with VX-680 at different concentrations for 24 hr and 48 hr. (A) Apoptotic cells were measured by Annexin V/PI staining. (B) Data summarized three independent experiments, **p < 0.01, ***p < 0.001, compared to control.

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