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Table 2 Expression of genes encoding SULF1, SULF2 and heparan sulfate proteoglycans in human cancer samples in comparison with their normal counterpart

From: SULFs in human neoplasia: implication as progression and prognosis factors

   Gene overexpressed in cancer samples in comparison to their normal tissue counterpart
Cancer sample type Datasets SULF1 SULF2 Syndecan 1-4 Glypican 1-6 CD44 isoforms containing the alternatively spliced exon v3 Agrin Betaglycan Perlecan Serglycin Testican 1-3
Leukemia 33 Yes No No No No No No Yes Yes Yes
Adrenal cancer 2 Yes No No No No No No No No No
Brain cancer 23 Yes Yes Yes Yes Yes Yes Yes Yes Yes No
Breast cancer 44 Yes Yes Yes No Yes No No No No Yes
Colon cancer 12 Yes No No No Yes No No No No No
Esophageal cancer 4 Yes No Yes Yes Yes Yes Yes Yes Yes No
Gastric cancer 5 Yes No No No No No No Yes No Yes
Head & Neck cancer 5 Yes Yes Yes Yes Yes No No Yes Yes No
Liver cancer 4 No Yes No No No No No No No No
Lung cancer 16 Yes No No No No Yes No No No Yes
Mesothelioma 3 Yes No No No No No No No No No
Pancreatic cancer 6 Yes No Yes No No No No Yes Yes Yes
Renal 11 Yes Yes No No Yes Yes No Yes No No
Sarcoma 11 Yes No No No No No No No No No
Skin cancer 1 Yes Yes No No No No No No No No
Testicular cancer 1 Yes Yes Yes Yes No Yes No No Yes No
  1. Expression data were obtained from the Oncomine Cancer Microarray database. Genes which were overexpressed in cancer cell samples in comparison with their normal counterpart are indicated in this table.