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Table 1 Univariate and multivariate proportional hazards analyses linking SULF2 expression to prognosis in HM cohort

From: SULFs in human neoplasia: implication as progression and prognosis factors

HM cohort (OS)
  Pronostic variable Proportional hazard ratio P-value
Univariate
Cox analysis
SULF2
ISS
4.08
1.73
0.007
0.001
Multivariate
Cox analysis
SULF2
ISS
3.65
1.70
0.028
0.001
Univariate
Cox analysis
SULF2
b2M
Alb
4.08
1.10
1.60
0.007
0.0001
0.04
Multivariate
Cox analysis
SULF2
b2M
Alb
3.49
1.10
1.35
0.03
0.0001
0.24
Univariate
Cox analysis
SULF2
HRS
4.08
2.30
0.007
0.002
Multivariate
Cox analysis
SULF2
HRS
4.11
2.31
0.01
0.002
Univariate
Cox analysis
SULF2
MS group
4.08
2.14
0.007
0.001
Multivariate
Cox analysis
SULF2
MS group
3.84
1.97
0.023
0.028
Univariate
Cox analysis
SULF2
IFM score
4.08
3.09
0.007
0.0001
Multivariate
Cox analysis
SULF2
IFM score
4.29
3.22
0.014
0.0001
Univariate
Cox analysis
SULF2
GPI
4.08
2.21
0.007
0.0001
Multivariate
Cox analysis
SULF2
GPI
4.47
2.25
0.011
0.0001
Univariate
Cox analysis
SULF2
MYEOV
4.08
3.16
0.007
0.05
Multivariate
Cox analysis
SULF2
MYEOV
3.71
2.76
0.026
0.08
Univariate
Cox analysis
SULF2
CD200
4.08
2.05
0.007
0.03
Multivariate
Cox analysis
SULF2
CD200
3.86
1.03
0.02
0.05
  1. Univariate analyses were done to screen for prognostic variables linked to SULF2 expression using Cox proportional hazards regression. The Cox model was also used for multivariate analysis to identify the most significant variables related to survival (OS): ISS (international staging system), b2M (beta-2 microglobulin), Alb (Albumin), HRS (High Risk Score), MS group (MMSET group), IFM score (IFM score), GPI (Growth Proliferation Index), MYEOV and CD200. P-values are in bold and italic when a significant result was obtained (p < 0.05).