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Figure 5 | Journal of Translational Medicine

Figure 5

From: Evaluation of the anti-angiogenic properties of the new selective αVβ3 integrin antagonist RGDechiHCit

Figure 5

Representative phase contrast photomicrographs of bovine aortic endothelial cells (ECs) are shown plated on Matrigel. Both c(RGDf[NMe]V) and RGDechiHCit inhibited hFN-induced tube formation. Microscopy revealed numbers of network projections (branches) formed in each group after 12 h of incubation. Data from three experiments in triplicate are summarized in the graph (* = p < 0.05 vs Basal; # = p < 0.05 vs hFN). Error bars show SEM. The black bar corresponds to 100 μm.

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