Figure 1
Baseline contractile function. A. Muscles from NBD treated dko mice (n = 9 muscles from n = 7 mice) exhibited a higher active developed force under baseline conditions (1.5 mM Ca2+, 4 Hz, 37°C) compared to muscles from vehicle treated control dko mice (n = 5 muscles from n = 4 mice). B. Maximum and minimum derivative of force (dF/dt) was higher in NBD treated mice. C. Time from stimulation to peak tension and time from peak tension to 90% relaxation were slightly, but not significantly, slower in non-treated muscles. * indicates a difference of P < 0.05 between the two groups.