CD4 and CD8 expression by TIL produced in plates vs bags. A, representative cytometry histograms of TIL produced in plates (upper panels) and bags (lower panels) stained for CD4 (left panels) and CD8 (right panels) from patient 06. White histograms correspond to isotypic controls. B, graphical representation of the percentage of CD8 (left) and CD4 (right) positive cells produced in plates vs bags. Circles correspond to the mean of the percentage of CD8 and CD4 positive cells obtained for each donors. For both graphics, left and right circles correspond to TIL expanded in plates and bags respectively. For each line the horizontal bar corresponds to the mean of the 8 donors. The difference between means is indicated by the p-value.