Figure 3

Journal-Concept Co-Occurrence Map for the Cancer Literature in 2009. The 20 most publishing journals (square nodes, colored according to research level) and the 250 most prevalent single- and multi-word concepts are mapped according to the strength of association between concept and journals; only the 30% most specific links are mapped. The map has three distinct zones. Clinical journals (e.g., Journal of Clinical Oncology, Cancer, Annals of Surgical Oncology) cluster at the top, with links to terms related to epidemiology and clinical trials (e.g., high risk, quality of life, overall survival, univariate analysis). Basic science and clinical research journals (e.g., Oncogene, Cancer Research) cluster at the bottom, with links to terms related to molecular biology and genetics (e.g., transcription factor, kinase, immune response, therapeutic target). The translational interface (from Cancer Science to Cancer Epidemiology) includes two sets of terms. One set reflects specific tumor types (e.g., prostate cancer, breast cancer, colorectal cancer.). The other set reflects specific translational techniques, with gene expression technologies on the left (e.g., PCR, western blot, microarrays) linked to clinical research journals (in orange) and ideas linked to the polysemic notion of risk on the right (e.g., cancer risk, family history, poor survival) linked to clinical mix journals (in green).