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Table 2 Results of post mortem pathological study in 3 groups*

From: Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy improves survival of gastric cancer with peritoneal carcinomatosis: evidence from an experimental study

 

Control (n = 14)

CRS (n = 12)*

CRS+HIPEC (n = 13)§

P

Ulcerative gastric cancer

100%

100%

100%

NA

Pyloric obstruction

100%

100%

100%

NA

Gastric perforation

28.6%

8.3%

8.3%

P = 0.246

Greater omentum cake

100%

removed

removed

NA

Liver metastases

100%

96.7%

38.5%

P = 0.000

Pulmonary metastases

0.0%

8.3%

53.8%

P = 0.000

Cancerous diaphragm

100%

100%

53.8%

P = 0.000

Upper abdominal wall cancer

100%

100%

84.6%

P = 0.128

Small intestine & mesentery seeding

100%

100%

61.5%

P = 0.002

Adrenal gland metastases

100%

100%

23.5%

P = 0.000

Kidney capsule invasion

100%

75.0%

30.8%

P = 0.000

Retroperitoneum metastases

100%

100%

76.9%

P = 0.038

Pelvic seeding

100%

100%

69.2%

P = 0.009

Urine retention

57.1%

75.0%

61.5%

P = 0.641

Bloody ascites

100%

100%

38.5%

P = 0.000

  1. * Two animals were excluded in CRS group, including 1 death due to anesthesia overdose on d 9 and another death due to postoperative hemorrhage on d 10.
  2. § One animal in CRS+HIPEC group was excluded due to anesthesia overdose death on d 9.
  3. NA: not applicable.