TGase-4 expression and the cells response to rhMDA-7. Left panel: Adhesion assay using ECIS 9600 system (A - PC-3pEF6 control cells; B - PC-3TGase4exp cells). Right panel (C): Cell adhesion assay using Rb modeling (ECIS 1600R, 4000 Hz). PC-3TGase4exp cells showed a significant increase in cell migration when compared with the PC-3pEF6 control cells (**, p < 0.01 vs the PC-3pEF6 control cells). MDA-7 inhibited cell adhesion in PC-3pEF6 cells (top left), a response lost in PC-3TGase4exp cells. * p < 0.01 vs no MDA-7 control PC-3pEF6 cells.