Figure 2

miR-21 and miR-155 are upregulated in differentiated CD8⁺ lymphocyte subsets. a) Unsupervised heatmap clustering of the expression levels of a selected set of microRNAs in each subset normalized to levels in naive cells (log2 fold change) (green: downregulated/red: upregulated). b) Expression levels of miR-21 and miR-155 in sorted human CD8⁺ T cell subsets were determined by single specific qPCR performed in triplicates, and are expressed as fold change relatively to levels in naive cells (n = 8; *: p < 0,05; **: p < 0,01).