Skip to main content
Figure 6 | Journal of Translational Medicine

Figure 6

From: Insertion of the human sodium iodide symporter to facilitate deep tissue imaging does not alter oncolytic or replication capability of a novel vaccinia virus

Figure 6

PET imaging of enhanced radiouptake in GLV-1h153-infected PANC-1 xenografts. Two × 107 PFU of GLV-1h153, GLV-1h68, or PBS was injected intratumorally into PANC-1 hindleg tumor-bearing mice. 124I-PET scanning was obtained 48 hours after infection and 1 hour after radiotracer administration. GLV-1h153-infected PANC-1 tumors were easily visualized, while no enhanced signal was seen in the PBS- or GLV-1h68 injected tumors. The stomach and thyroid were also imaged due to native NIS expression, and the bladder due to tracer excretion.

Back to article page

Journal of Translational Medicine

ISSN: 1479-5876

Contact us