In vitro migration of cytotoxic T lymphocyte derived from a colon carcinoma patient is dependent on CCL2 and CCR2

Table 1 CCR2 expression by T-cell lines established from tumor infiltrating lymphocytes of CRC tissues.

Patient^a		T cell phenotype	Expression of CCR2 (% positive cells)^b
#	Dukes' Disease Stage
296674	A	CD4	58.8
298884	B	CD4/CD8	68
1003485	B	CD4/CD8	48.2
05193	B	CD4/CD8	27.4

^aRepresentative data from 4 patients whose T cells were positive for CCR2 expression.
^bCCR2 expression determined by FACS analysis. Data represented are from a single experiment and the Results were confirmed in at least two independent experiments.

ISSN: 1479-5876