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Figure 6 | Journal of Translational Medicine

Figure 6

From: Shipping blood to a central laboratory in multicenter clinical trials: effect of ambient temperature on specimen temperature, and effects of temperature on mononuclear cell yield, viability and immunologic function

Figure 6

Internal temperature change over time in containers designed for shipping blood specimens. Ten water-filled vacutainer vials were pre-warmed to 37°C placed inside the JVI Control Temp shipping container or in the Safeguard (SG) shipping container, surrounded with pre-warmed gel packs, placed inside an insulated corrugated cardboard container, and sealed with tape for testing at low external temperatures. Internal package temperatures were continuously monitored inside JVI and SG shipping containers while placed (A) at a constant low temperature of 4°C for 22 hours followed by 22°C for 8 hours; (B) outdoors in ambient winter temperatures for 16 hours; and (C) outdoors in ambient winter temperatures for 18 hours followed by placement of package at 22°C for 20 hours. (green diamond) External package (ambient) temperature; internal package temperatures: (red triangle), JVI with 37°C thermal pack; (purple square), SG with 37°C thermal pack; (blue triangle), JVI with 22°C thermal pack; (blue square), SG with 22°C thermal pack. Solid black line indicates 15°C; dashed line denotes 0°C.

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