Figure 4From: Shipping blood to a central laboratory in multicenter clinical trials: effect of ambient temperature on specimen temperature, and effects of temperature on mononuclear cell yield, viability and immunologic functionCD8 T cells show greater susceptibility to apoptosis than CD4 T cells. The percentage of cells in different stages of apoptosis was evaluated for CD4 and CD8 T cell populations. (A) Percentage of CD4 lymphocytes in early stages of apoptosis (Annexin V+, 7AAD-) and (B) late stages of apoptosis (Annexin V+, 7AAD+); (C) CD8 lymphocytes in early stages of apoptosis (Annexin V+, 7AAD-) and (D) late stages of apoptosis (Annexin V+, 7AAD+). Shaded region indicates control condition as described in Figure 3.Back to article page