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Table 3 Diagnostic accuracy of sFlt-1 and VEGF-A levels for septic shock development

From: Time-course of sFlt-1 and VEGF-A release in neutropenic patients with sepsis and septic shock: a prospective study

Biomarker

Time-point

sFlt-1

VEGF-A

Fever onset

  

AUC *

0.61 (0.41-0.81); P = 0.81

0.58 (0.38-0.77); P = 0.47

48 hours after fever onset

  

AUC *

0.87 (0.73-1.00); P < 0.01

0.76 (0.55-0.97); P = 0.02

  1. * AUC: area under ROC curve; sFlt-1 and VEGF-A thresholds correspond to the median value for each time point. AUC expressed with 95% confidence interval (CI95%)
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Journal of Translational Medicine

ISSN: 1479-5876

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