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Figure 3 | Journal of Translational Medicine

Figure 3

From: Poly I: C-activated dendritic cells that were generated in CellGro for use in cancer immunotherapy trials

Figure 3

The induction of antigen-specific T cells. DCs that were generated in CellGro or RPMI+5% human AB serum were activated using the tested maturation stimuli and subsequently used as stimulators for the induction of antigen-specific T cells. The frequency of antigen-specific T cells was analyzed using intracellular IFNγ staining. A, B. Induction of HLA-A2 influenza MP-specific CD8 T cells. The summary (A) and representative staining (B) of five independent experiments are shown. C. Induction of HLA-A2 influenza MP-, CEF peptide mix- and PSA peptide mix-specific T cells using DCs that were generated in CellGro and activated using Poly I:C. Representative dot plots of five independent experiments are shown.

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