Lansoprazole as a rescue agent in chemoresistant tumors: a phase I/II study in companion animals with spontaneously occurring tumors

Table 9 Characteristics and outcome of feline patients treated chemotherapy alone for chemoresistant cancers

PATIENT	AGE	TUMOR	PREV. TREATMENT	THERAPY	OUTCOME (MONTHS)
DSH	10	BREAST CARCINOMA	DOXORUBICIN CARBOPLATIN	CARBOPLATIN	PD 1
DSH	12	FSA	CARBOPLATIN	CARBOPLATIN	PR 2
DSH	10	ORAL SCC	MITOXANTRONE CARBOPLATIN	MITOXANTRONE	PD 1
DSH	12	ORAL FSA	DOXORUBICIN CARBOPLATIN	CARBOPLATIN	PD 1
DSH	12	LSA	MADISON MOPP	MOPP	PR 2
DSH	7	FSA	SURGERY, DOXORUBICIN CARBOPLATIN	CARBOPLATIN	PD 1
NORVEGIAN	7	LSA	MADISON MOPP	MOPP	PD 2

Abbreviations: DSH: domestic short hair; FSA: fibrosarcoma; LSA: lymphosarcoma; MOPP: mechlorethamine, oncovin (vincristine), prednisone, procarbazine; SCC: squamous cell carcinoma. +: still alive.
Drugs schedule: doxorubicin 30 mg/m² every 21 days (pending hematological, cardiac and renal evaluation) up to 6 doses, carboplatin 210 mg/m² every 21 days, mitoxantrone 6 mg/m² every 21 days. For Madison and MOPP protocols see table 4 and 5.

ISSN: 1479-5876