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Table 2 Modified Eastern Cooperative Oncology Group evaluation

From: Lansoprazole as a rescue agent in chemoresistant tumors: a phase I/II study in companion animals with spontaneously occurring tumors

Toxicity/Grade Signs Duration
Hospitalization Days
0 0
1 1
2 2-3
3 4-5
4 ≥ 5
Neutropenia  
0 ≤ 500 neutrophils/mL
1 1,500-2,500 neutrophils/mL
2 ≥ 2,500 neutrophils/mL
3 500-999 neutrophils/mL
4 1,000-1,499 neutrophils/mL
Anorexia  
0 None
1 Inappetance
2 Anorexia ≤ 3 days duration
3 Anorexia > 3 days but < 5 days
4 Anorexia ≥ 5 days 10% weight loss
Vomiting  
0 None
1 Nausea
2 Sporadic, self-limiting
3 1-5 episodes per day, < 2 days
4 6-10 episodes per day, hospitalized
Diarrhea  
0 None
1 Soft stools, responds to dietary modification
2 1-4 watery stools per day, < 2 days
3 4-7 watery stools per day or > 2 days
4 > 7 watery stools per day or bloody, hospitalized
Infection  
0 None
1 No medication
2 Required medication
3 Debilitating
4 Threatening