Table 3 Up regulated genes of MDA-MB-231 cells treated with MAb9E10 antibody 24 and 48 hours (Fold change)
From: ATP synthase ecto-α-subunit: a novel therapeutic target for breast cancer
Symbol | UniGene | Description | 24 h group | 48 h group | |
|---|---|---|---|---|---|
1 | FOXO1 | Hs.370666 | Forkhead box O1 | 17.95 | 30.64 |
2 | CASP9 | Hs.329502 | Caspase 9, apoptosis-related cysteine peptidase | 2.67 | 17.37 |
3 | NDUFS3 | Hs.502528 | NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30 kDa (NADH-coenzyme Q reductase) | 7.48 | 10.73 |
4 | HSPA1B | Hs.274402 | Heat shock 70 kDa protein 1B | 7.68 | 9.62 |
5 | COL4A3 | Hs.570065 | Collagen, type IV, alpha 3 (Goodpasture antigen) | 2.23 | 8.86 |
6 | NFKB1 | Hs.654408 | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 6.71 | 6.3 |
7 | F2R | Hs.482562 | Coagulation factor II (thrombin) receptor | 6.59 | 5.38 |
8 | CRYAB | Hs.408767 | Crystallin, alpha B | 6.62 | 4.97 |
9 | SOCS2 | Hs.485572 | Suppressor of cytokine signaling 2 | 4.09 | 4.89 |
10 | NOD2 | Hs.592072 | Nucleotide-binding oligomerization domain containing 2 | 6.46 | 4.88 |
11 | PIK3R2 | Hs.371344 | Phosphoinositide-3-kinase, regulatory subunit 2 (beta) | 1.72 | 4.75 |
12 | PRKCE | Hs.580351 | Protein kinase C, epsilon | 2.83 | 4.66 |
13 | CASP7 | Hs.9216 | Caspase 7, apoptosis-related cysteine peptidase | 4.85 | 4.43 |
14 | TBX3 | Hs.714737 | T-box 3 | 3.6 | 4.24 |
15 | BIRC8 | Hs.348263 | Baculoviral IAP repeat containing 8 | 2.88 | 4.08 |
16 | PIM2 | Hs.496096 | Pim-2 oncogene | 4.23 | 3.79 |
17 | HSPB1 | Hs.520973 | Heat shock 27 kDa protein 1 | 1.75 | 3.76 |
18 | IL31RA | Hs.55378 | Interleukin 31 receptor A | 3.46 | 3.46 |
19 | MADD | Hs.82548 | MAP-kinase activating death domain | 2.06 | 3.43 |
20 | PEA15 | Hs.517216 | Phosphoprotein enriched in astrocytes 15 | 7.8 | 3.38 |
21 | BNIP1 | Hs.145726 | BCL2/adenovirus E1B 19 kDa interacting protein 1 | 5.48 | 3.28 |
22 | CASP14 | Hs.466057 | Caspase 14, apoptosis-related cysteine peptidase | 7.09 | 3.09 |
23 | MAL | Hs.80395 | Mal, T-cell differentiation protein | 2.42 | 3.04 |